Measurement / residue studycited by the Tayebat archiveabstract checked A-FSH-17 standard review

Feed preservatives in farmed fish

Levels of synthetic antioxidants (ethoxyquin, butylated hydroxytoluene and butylated hydroxyanisole) in fish feed and commercially farmed fish.

Overview

Lundebye AK et al.. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2010 · PMID 20931417 · DOI 10.1080/19440049.2010.508195

A portion of farmed salmon gave up to 75% of the acceptable daily intake of BHT.

Does the study support the specific claim? Partly · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Measure antioxidants.

How was the study done?

Lab analysis.

How many people, animals or samples were studied?

Norwegian farmed fish.

What was actually found?

Below ADI per portion.

How large was the observed effect?

BHT up to 75% ADI.

What do the results mean in everyday life?

Within limits.

What are the study's limitations?

2010 data.

What does it say about Elawady's specific claim?

Weak support.

Do the results apply to Germany and Europe?

High.

What can explicitly not be concluded from this study?

Harm.

Scientific in-depth review

1. Full reference

Authors
Lundebye AK, Hove H, Måge A, Bohne VJ, Hamre K
Journal
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
Year
2010
Identifier
PMID 20931417 DOI 10.1080/19440049.2010.508195
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

not stated in abstract/record

2. Research question

Levels of ethoxyquin, BHT, BHA in farmed fish?

3. Study design and population

Study design
Measurement / residue study – Measurement of synthetic antioxidants in feed and farmed fish fillets with exposure estimate
Population

Farmed salmon, halibut, cod, rainbow trout; feed

Country

Norway

Period

published 2010

Sample size

not stated

4. Methods and endpoints

Exposure / intervention

Farmed species

Comparator

ADI

Endpoints

Concentrations; % ADI

5. Actual results

Results

Highest in salmon: BHT 7.60, EQ 0.17, BHA 0.07 mg/kg; EQ dimer >10x parent; 300 g portion: EQ <= 15% ADI, BHT up to 75% ADI (60 kg adult).

Absolute risks

not reported

Authors' conclusion

Exposure calculated; no exceedance of ADI from one portion.

6. Strengths

  • Exposure vs ADI

7. Weaknesses

  • 2010 data

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
low

9. Assessment of the statistical interpretation

10. Relevance to the specific claim

Context for C-FSH-02.

11. Independent contrary findings

Itself (below ADI).

12. Transferability to Germany and Europe

High (Norway).

13. Overall methodological judgement

Shows exposures within ADI.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biaslow
Precision of resultsnot applicable
Directnessdirect
Reproducibilityunknown
Consistency with the overall evidenceunknown
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

Ethoxyquin dimer toxicology.

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Bibliography only.

A. What was actually studied?

Feed antioxidants.

B. What did the authors find?

Below ADI per portion.

C. What conclusions do the authors themselves draw?

As found.

D. What does the archive derive from it?

Implied additional contaminant.

E. Is this derivation scientifically justified?

Archive does not mention that intakes were below ADI.

Adequacy of the interpretation (by the archive)
not applicable