Mostly false Scientifically refuted Certainty of evidence: moderate provisional C-SRC-65

Pregnant women develop health problems because pregnancy causes cortisol deficiency and raised intra-abdominal pressure.

Safety note: Pregnant women should not replace prenatal care, prescribed medication (e.g. for blood pressure, thyroid or diabetes) or recommended supplements such as folic acid with this explanation. Warning signs such as severe headache, swelling, visual disturbance, bleeding or abdominal pain need urgent medical attention.
In short: Mostly false: normal pregnancy raises cortisol about threefold rather than causing a deficiency; abdominal pressure does rise in late pregnancy, but whether it causes complications is unproven.
Conclusion: Cortisol rises in pregnancy; abdominal pressure is a plausible but unproven factor, so the explanation is mostly wrong.

Original statement

في الرئه زاد واحد بيكح كتير ليه الست الحامل بتضرب وليه الست الحامل بتظهر عندها المشاكل لانها بتخش في نقص الكورتيزون وارتفاع في ضغط البطن يعني الحمل بيجي >> بيعمل اضطراب في في اكسس في مسار

verbatim according to source. Translation by the project; the Arabic wording is authoritative.

Translation

Pregnant women develop health problems because pregnancy causes cortisol deficiency and raised intra-abdominal pressure.

Origin

Source status
Video transcript (own words)
Attribution
Elawady (machine transcript)
Video
الضغط الجوي atmospheric pressure وضغط البطن وعلاقته بأعراضك #ضياء_العوضي (Open source)
Published
9 January 2026
Timestamp
0:00:35 (location in the original video’s automatic YouTube caption track; confirms where the words occur, not who speaks)
Attribution uncertainty
Transcript is YouTube CC or machine-generated (no timestamps); wording may contain speech-recognition errors. Speaker attribution within live streams/podcasts is not marked in the transcript; the excerpt was judged to be Elawady's own speech from context. Recurrence = number of archive transcripts matching the keyword pattern ['الحامل|حامل', 'كورتيزون|ضغط البطن'] (approximate; includes re-uploads/clips; 10 distinct text passages).
Claimed mechanism

Cortisol deficiency and raised intra-abdominal pressure during pregnancy.

Claimed health effect

Health problems in pregnancy.

Population concerned

Pregnant women.

Geographic restriction by Elawady

none found; he does not limit this statement to a country or to a production system

Diverging source versions

Source status
Video transcript (own words)
Attribution
Elawady (machine transcript)
Video
ارتفاع ضغط البطن والاضطراب الهرموني وظهور كل ماهو مناعي #ضياء_العوضي (Open source)
Published
10 January 2026
Timestamp
not available (transcript has no timings)
Attribution uncertainty
Further video in which the same statement recurs; no excerpt recorded. Archive transcript without timestamps.

Scientific assessment

Mostly false – Essential parts of the statement are not supported by the evidence or are strongly exaggerated.

Certainty of evidence: moderate – Further research may still affect the assessment.

1. What was claimed?

Pregnant women develop health problems because pregnancy causes cortisol deficiency and raised intra-abdominal pressure.

2. What is demonstrably correct?

The growing uterus raises intra-abdominal pressure in late pregnancy; a review describes this as a chronically compensated physiological state to which most women adapt, notes that normal values are lacking and treats a link with pre-eclampsia as an unproven hypothesis (I-INTB-23). A small Sri Lankan study measured intra-abdominal pressure of about 12.7 mmHg at term, in the range defined as intra-abdominal hypertension in non-pregnant people, and somewhat higher values in women with high blood pressure (I-SRC-119; cross-sectional, 70 women, not causal).

3. What is wrong or exaggerated?

Pregnancy does not cause cortisol deficiency: total plasma cortisol rose progressively to about three times control levels in the third trimester and free cortisol rose 1.6-fold (I-INTB-22). Pregnancy complications (e.g. pre-eclampsia, gestational diabetes, anaemia) have multiple established causes; a single explanation by 'cortisol deficiency and abdominal pressure' is not supported. Endocrine reviews describe normal pregnancy as a state of sustained physiological hypercortisolaemia, with free cortisol rising progressively (I-SRC-129).

4. What remains unclear?

Whether raised intra-abdominal pressure contributes to pre-eclampsia or other complications is not known (I-INTB-23).

5. Which studies support it?

I-INTB-23, I-SRC-119 (only for the narrow point that intra-abdominal pressure rises in late pregnancy; neither shows that it causes complications or concerns cortisol).

6. Which studies contradict it?

I-INTB-22, I-SRC-129.

7. What applies to Germany and Europe?

Not region-specific.

8. What is known about Egypt?

Not region-specific.

9. What practical conclusion is appropriate?

Pregnant women should attend regular prenatal care; symptoms such as headache, swelling, high blood pressure or abdominal pain need medical assessment.

Assessment details

Rationale for certainty of evidence

Longitudinal measurements show that total and free cortisol rise, not fall, during pregnancy (I-INTB-22); this is a small study but consistent with established physiology. Raised intra-abdominal pressure in pregnancy is plausible but under-studied, and its role in complications is a hypothesis (I-INTB-23).

Source quality

Machine transcript of a live stream; wording may contain recognition errors; meaning checked in context.

Regional transferability

Universal physiology.

Individual exceptions

Rare women have adrenal insufficiency in pregnancy; this is a specific disease, not a general effect of pregnancy.

Regional scope of the claim
general (biological/medical)
Last reviewed
26 October 2026 provisional

Scientific evidence in detail

Scientifically refuted – High-quality evidence shows the opposite, or the claim contradicts well-established physiology.

Research question: Do pregnant women develop health problems because pregnancy causes cortisol deficiency and raised intra-abdominal pressure?

Research question in detail (PECO)
Population
Pregnant women
Intervention or exposure
Pregnancy-related changes in cortisol and intra-abdominal pressure
Comparison
Non-pregnant state / normotensive pregnancy
Geographic scope
universal biology
Outcomes
  • Plasma and free cortisol
  • Intra-abdominal pressure
  • Pregnancy complications (e.g. hypertension)

Study results as reported by the authors. Our assessment follows below.

What speaks for the claim?

  • Belly pressure in late pregnancy and high blood pressure

    Jayasundara S et al.. PLoS One 2023 · PMID 37851647 · DOI 10.1371/journal.pone.0284230 Cross-sectional studyfull text checkednewly added

    Cross-sectional IAP study in 70 women having caesarean delivery (full text).

    Actual result
    Term IAP 12.7 mmHg in normotensive women (intra-abdominal-hypertension range for non-pregnant people); hypertensive women +1.6 mmHg antepartum (p=0.268), +2.5 mmHg postpartum (p=0.018).
    Methodological quality
    low (small, cross-sectional; reporting errors)
    Relevance
    direct for the pressure part only
    Limitations
    No causal inference; no cortisol data.

    Original publication

  • Abdominal pressure in pregnancy

    Chun R, Kirkpatrick AW. Ann Intensive Care 2012 · PMID 22873421 · DOI 10.1186/2110-5820-2-S1-S5 Narrative reviewfull text, structured risk-of-bias assessment

    Review of IAP in pregnancy.

    Actual result
    Pregnancy regarded as a chronically compensated state of intra-abdominal hypertension; link with pre-eclampsia hypothetical.
    Methodological quality
    low (narrative)
    Relevance
    indirect
    Limitations
    Few data.

    Original publication

What speaks against the claim?

  • Cortisol rises during pregnancy

    Jung C et al.. J Clin Endocrinol Metab 2011 · PMID 21367926 · DOI 10.1210/jc.2010-2395 Cohort studyabstract checked

    Longitudinal cortisol study.

    Actual result
    Total plasma cortisol about 3-fold higher in the third trimester; free cortisol 1.6-fold.
    Methodological quality
    moderate (small but consistent with physiology)
    Relevance
    direct
    Limitations
    Small.

    Original publication

  • Cortisol rises in normal pregnancy

    Lee JH et al.. Rev Endocr Metab Disord 2023 · PMID 35816262 · DOI 10.1007/s11154-022-09745-6 Narrative reviewabstract checkednewly added

    Endocrine review of adrenal function in pregnancy.

    Actual result
    Pregnancy is a state of sustained physiological hypercortisolaemia; free cortisol rises progressively.
    Methodological quality
    moderate (narrative, consistent)
    Relevance
    direct
    Limitations
    Narrative.

    Original publication

What does the overall evidence say?

Editorial assessment based on the studies above – not itself a study result.

Which position is better supported?

Cortisol rises in pregnancy; raised abdominal pressure is real in late pregnancy but its role in complications is unproven.

Why some studies weigh more

Direct measurements of cortisol outweigh the asserted deficiency; the IAP evidence is weak and cross-sectional.

Is a causal relationship established? Not established No evidence that pregnancy problems are caused by cortisol deficiency; IAP causality untested.

Remaining uncertainty

Whether IAP contributes to hypertensive disorders of pregnancy.

Justified conclusion

The cortisol part is wrong; the abdominal-pressure idea is a hypothesis with weak support; pregnancy complications have multiple established causes.

Does this depend on the country?
General biological effects
Universal physiology.
Eating habits
Not applicable.
Origin of the food
Not applicable.
Contaminants
Not applicable.
National production conditions
Not applicable.
Legal rules
Not applicable.
Actual monitoring data
No Egyptian data.

A regional difference that changes the conclusion is not supported by robust data.

Statistical re-check
  • Plausibility of reported CI and interpretation of regression coefficient – Abstract postpartum CI (11.6-13.8) excludes its own mean 7.3 (copy error; full text 6.5-8.0); '1.6 times higher IAP' is an additive 1.6 mmHg (~13%), not significant recalculated
Certainty of the overall evidence (GRADE, simplified)
Main outcome
Maternal cortisol level in pregnancy
Starting level
low (observational studies)
Reasons for downgrading
  • imprecision: small longitudinal studies
Reasons for upgrading
  • large, consistent effect (about threefold rise)
Result
moderate

Simplified assessment by a single reviewer, following the GRADE approach; not a formal GRADE panel. GRADE rates the body of evidence for one outcome, not individual studies.

Clinical guidelines and official statements checked
  • WHO: WHO recommendations on antenatal care for a positive pregnancy experience (2016) · Original publication
    Publication page: guideline covering nutrition, maternal and fetal assessment, preventive measures and common physiological symptoms in antenatal care (detailed recommendations not read).
Search strategy

Documented literature searches for this review (search strings in the original database syntax).

DatabaseDateSearchLooking forHitsIncluded
Europe PMC26 October 2026(cortisol) AND (pregnancy) AND ("adrenal insufficiency" OR "lower cortisol" OR "reduced cortisol" OR hypocortisolism) AND (preeclampsia OR "pre-eclampsia" OR complications)supporting evidence2091
Europe PMC26 October 2026("intra-abdominal pressure" OR "intraabdominal pressure") AND (pregnan*) AND (preeclampsia OR "pre-eclampsia" OR hypertension)supporting evidence2204
PubMed26 October 2026maternal cortisol across pregnancy longitudinal free cortisol trimester referencecontradicting evidence0
PubMed26 October 2026adrenal insufficiency in pregnancy diagnosis management reviewboth directions63
Europe PMC26 October 2026(cortisol) AND (pregnancy OR pregnant) AND (longitudinal OR trimester) AND ("free cortisol" OR "salivary cortisol" OR "hair cortisol") AND (increase OR rise)contradicting evidence2809
WHO website26 October 2026WHO recommendations on antenatal care for a positive pregnancy experience (publication page)guidelines1

Open questions

Prospective IAP measurements and hypertensive disorders.

How deeply was this checked?

4 linked studies: 2 checked in full text (1 of them with a structured risk-of-bias assessment), 2 on the basis of the abstract, 0 bibliographically only. No formal assessment with two independent reviewers and no independent human expert review has taken place yet.

Last scientific review: 26 October 2026

History of the verdict
  1. 25 October 2026 · Phase 1 · Initial assessment: Mostly false (moderate)
  2. 26 October 2026 · Phase 4 (systematic evidence review) · Re-examined with extended evidence; verdict unchanged: Mostly false (moderate)
    Endocrine review and an IAP study (with reporting errors) refine both parts; verdict and certainty unchanged.
    New sources: I-SRC-119 I-SRC-129

In plain language

Dr. Elawady said pregnant women get health problems because pregnancy lowers cortisol and raises the pressure in the belly. Measurements show the opposite for cortisol: it rises about threefold during pregnancy. The growing womb may raise belly pressure, and researchers have asked whether this plays a role in some complications, but this is not proven. Pregnancy problems have many causes and need regular medical check-ups.

Studies on this claim

Studies supporting the claim (0)

No studies in this group.

Studies contradicting or limiting the claim (2)

  • Cortisol rises during pregnancy

    Jung C et al.. J Clin Endocrinol Metab 2011 · PMID 21367926 · DOI 10.1210/jc.2010-2395
    Cohort studyindependent cross-checkabstract checked★ key study

    Total cortisol rose about threefold and free cortisol 1.6-fold by the third trimester.

    Cortisol rises about 3-fold.

    Does the study support the specific claim? No · Methodological quality: moderate · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Measure cortisol in pregnancy

    How was the study done?

    Longitudinal study

    How many people, animals or samples were studied?

    20 pregnant women + controls

    What was actually found?

    Cortisol rises progressively

    How large was the observed effect?

    3-fold total; 1.6-fold free

    What do the results mean in everyday life?

    In normal pregnancy the body makes more cortisol, not less.

    What are the study's limitations?

    Small study; abstract only

    What does it say about Elawady's specific claim?

    Contradicts 'cortisol deficiency in pregnancy'.

    Do the results apply to Germany and Europe?

    High

    What can explicitly not be concluded from this study?

    Does not address rare adrenal insufficiency in pregnancy.

    Scientific details →

  • Cortisol rises in normal pregnancy

    Lee JH et al.. Rev Endocr Metab Disord 2023 · PMID 35816262 · DOI 10.1007/s11154-022-09745-6
    Narrative reviewindependent cross-checkabstract checked

    Normal pregnancy raises cortisol, including the free active form; true adrenal insufficiency is a separate, rare disease.

    Pregnancy is a state of physiological hypercortisolaemia.

    Does the study support the specific claim? No · Methodological quality: moderate · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Review adrenal function in pregnancy

    How was the study done?

    Narrative review

    How many people, animals or samples were studied?

    not applicable

    What was actually found?

    Physiological high cortisol in pregnancy

    How large was the observed effect?

    not applicable

    What do the results mean in everyday life?

    Pregnancy does not cause cortisol deficiency

    What are the study's limitations?

    Narrative

    What does it say about Elawady's specific claim?

    Contradicts the cortisol part

    Do the results apply to Germany and Europe?

    High

    Scientific details →

Studies with mixed or unclear results (2)

  • Abdominal pressure in pregnancy

    Chun R, Kirkpatrick AW. Ann Intensive Care 2012 · PMID 22873421 · DOI 10.1186/2110-5820-2-S1-S5
    Narrative reviewindependent cross-checkfull text, structured risk-of-bias assessment

    Abdominal pressure is probably raised near term, but most women adapt to it; any role in pre-eclampsia is only a hypothesis. Cortisol is not discussed.

    Raised IAP in pregnancy plausible; causal role unproven.

    Does the study support the specific claim? Partly · Methodological quality: low · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Review IAP in pregnancy

    How was the study done?

    Narrative review

    How many people, animals or samples were studied?

    not applicable

    What was actually found?

    Few IAP data in pregnancy (e.g. median 22 mmHg at term, 16 mmHg after delivery); pregnancy considered a compensated state; pre-eclampsia link hypothetical

    How large was the observed effect?

    not applicable

    What do the results mean in everyday life?

    The growing womb may raise abdominal pressure, but whether this causes complications is not known.

    What are the study's limitations?

    Narrative review with a single case; no systematic search; measurement methods unvalidated in pregnancy

    What does it say about Elawady's specific claim?

    Partly plausible; does not support his general explanation.

    Do the results apply to Germany and Europe?

    Universal

    What can explicitly not be concluded from this study?

    Cannot conclude that abdominal pressure (or cortisol deficiency, not studied) explains pregnancy health problems

    Scientific details →

  • Belly pressure in late pregnancy and high blood pressure

    Jayasundara S et al.. PLoS One 2023 · PMID 37851647 · DOI 10.1371/journal.pone.0284230
    Cross-sectional studyindependent cross-checkfull text checked

    Pressure inside the abdomen was high at term, and somewhat higher in women with high blood pressure; the study was small.

    IAP is high at term and possibly linked to hypertension (small cross-sectional study); no causal evidence.

    Does the study support the specific claim? Partly · Methodological quality: low · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Measure belly pressure in pregnancy

    How was the study done?

    Cross-sectional study

    How many people, animals or samples were studied?

    70 women

    What was actually found?

    High pressure at term; association with hypertension uncertain

    How large was the observed effect?

    +1.6 mmHg antepartum (not significant)

    What do the results mean in everyday life?

    Belly pressure rises in pregnancy; its role in disease is unproven

    What are the study's limitations?

    Small; reporting errors

    What does it say about Elawady's specific claim?

    Supports only the plausibility of the pressure idea

    Do the results apply to Germany and Europe?

    Moderate

    What can explicitly not be concluded from this study?

    That pressure causes complications

    Scientific details →

Regional context

Germany / EU

Not region-specific.

Egypt

Not region-specific.

What applies in my country?

General scientific assessment

Mostly false Cortisol rises in pregnancy; abdominal pressure is a plausible but unproven factor, so the explanation is mostly wrong.

This statement concerns biological or medical relationships. The scientific assessment above applies regardless of the country; country-specific food data do not change it.

References

  1. A longitudinal study of plasma and urinary cortisol in pregnancy and postpartum.. Jung C et al.. J Clin Endocrinol Metab 2011 · PMID 21367926 · DOI 10.1210/jc.2010-2395
  2. Adrenal insufficiency in pregnancy: Physiology, diagnosis, management and areas for future research.. Lee JH et al.. Rev Endocr Metab Disord 2023 · PMID 35816262 · DOI 10.1007/s11154-022-09745-6
  3. Intra-abdominal pressure, intra-abdominal hypertension, and pregnancy: a review.. Chun R, Kirkpatrick AW. Ann Intensive Care 2012 · PMID 22873421 · DOI 10.1186/2110-5820-2-S1-S5
  4. The association between maternal intra-abdominal pressure and hypertension in pregnancy.. Jayasundara S et al.. PLoS One 2023 · PMID 37851647 · DOI 10.1371/journal.pone.0284230

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